Conclusions
LS is a chronic inflammatory disease that is often localized to the genital skin and urethra in men. It has an association with squamous cell carcinoma and early biopsy to confirm diagnosis, as well as long-term follow-up is recommended. For cases isolated to the prepuce, glans, and meatus, topical steroids are recommended. More proximal urethral disease is difficult to treat and urethral reconstruction may be necessary. When urethroplasty is performed, either 1- or 2-stage procedures are acceptable depending on the presentation and tissue replacement with buccal mucosa grafts is the standard. Genital skin should not be used in either graft or flap based repairs in patients with LS.